Browsing NTNU Open by Author "Hingorani, Aroon D."

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    • Mendelian randomization for studying the effects of perturbing drug targets 

      Gill, Dipender; Georgakis, Marios K.; Walker, Venexia M.; Schmidt, Amand F.; Gkatzionis, Apostolos; Freitag, Daniel F.; Finan, Chris; Hingorani, Aroon D.; Howson, Joanna M.M.; Burgess, Stephen; Swerdlow, Daniel I.; Davey Smith, George; Holmes, Michael V.; Dichgans, Martin; Scott, Robert A.; Zheng, Jie; Psaty, Bruce M.; Davies, Neil Martin (Peer reviewed; Journal article, 2021)
      Drugs whose targets have genetic evidence to support efficacy and safety are more likely to be approved after clinical development. In this paper, we provide an overview of how natural sequence variation in the genes that ...

    • Plasma protein patterns as comprehensive indicators of health 

      Williams, Stephen; Kivimäki, Mika; Langenberg, Claudia; Hingorani, Aroon D.; Casas, Juan P.; Bouchard, Claude; Jonasson, Christian; Sarzynski, Mark A.; Shipley, Martin J.; Leigh, Alexander; Ash, Jessica; Bauer, Tim; Chadwick, Jessica; Kirk DeLisle, Robert; Datta, Gargi; Hagar, Yolanda; Hinterberg, Michael; Ostroff, Rachel; Weiss, Sophie; Ganz, Peter; Wareham, Nicholas J. (Journal article; Peer reviewed, 2019)